| Name | Deductibility Code |
| Ability Building Services Foundation Inc. | -- |
| Ability Building Services Inc. | -- |
| Abundant Life Ministries of Yankton South Dakota | -- |
| Areawide Business Council Incorporated | -- |
| Benedictine Health Foundation | -- |
| Benedictine Health System | -- |
| Big Friend-Little Friend Inc. | -- |
| Contact-Referral Center for Human Resources | -- |
| Edgar W Freeman Charitable Trust 17174 W-555 First Natl Bank Bldg | -- |
| Family Education and Counseling Center Inc. | -- |
| First Night Yankton Inc. | -- |
| Friends of Gavins Point National Fish Hatchery Inc. | -- |
| Gayville Community Cemetery | 6 |
| Health Management Services | -- |
| Heartland Humane Society Inc. | -- |
| Historic Downtown Yankton Inc. | -- |
| House of Mary Shrine Lewis and Clark Lake | -- |
| Just for Kids | -- |
| Keep Yankton Beautiful Inc. | -- |
| Lewis and Clark Health Education and Service Agency | -- |
| Lewis and Clark Mental Health Center | -- |
| Lewis and Clark Theatre Company Inc. | -- |
| Living Water Christian Fellowship | -- |
| Missouri River Natural Resources Committee | -- |
| Missouri Valley Christian Academy | -- |
| Missouri Valley Foundation for Health Care | -- |
| Missouri Valley Railroad Club Inc. | -- |
| National Field Archery Association Foundation | -- |
| Nursing Students Association of South Dakota | -- |
| Prairieland Housing Development | -- |
| Rademacher Cemetery Corporation | 6 |
| Regional Technical Education Center Inc. | -- |
| River City Gymnastics Club | -- |
| Robert R and Charlene L Zylstra Family Foundation Inc. | 4 |
| Sacred Heart Rural Health Clinics Inc. | -- |
| Sioux Empire Youth Symphony | -- |
| South Dakota and Upper Midwest Black History Museum | 4 |
| South Dakota Corrections Association | -- |
| Southeast Job Link Inc. | -- |
| St. Columbkills North Cemetery Association | 6 |
| Tri-State Old Iron Association Inc. | -- |
| United Church of Christ Congreg of Yankton Foundation | -- |
| United Way and Volunteer Services of Greater Yankton | -- |
| Vermillion Beautiful Inc. | -- |
| Xyz Corporation | -- |
| Yankton Area Arts Association | -- |
| Yankton Area Banquet | -- |
| Yankton Area Concert Association | -- |
| Yankton Area Crime Stoppers Inc. | -- |
| Yankton Area Ice Association | -- |
| Yankton Area Literacy Council | -- |
| Yankton Area Riverboat Days Inc. | -- |
| Yankton Area Search and Rescue Inc. | -- |
| Yankton Area Senior Citizens Center Inc. | -- |
| Yankton Area Youth Soccer Association | -- |
| Yankton Band Boosters | -- |
| Yankton Baseball Association | -- |
| Yankton Basketball Inc. | -- |
| Yankton Childrens Choir | -- |
| Yankton Childrens Theatre Company | -- |
| Yankton Christian School | -- |
| Yankton College | -- |
| Yankton Community Transportation Program Inc. | -- |
| Yankton County Historical Society | -- |
| Yankton Education and Health Care Fund Inc. | -- |
| Yankton Regional Council on Aging | -- |
| Yankton Rotary Foundation | -- |
| Yankton Rural Area Health Education Center | 4 |
| Yankton Rural Fire Association Inc. | -- |
| Yankton School District 63-3 Foundation | -- |
| Yankton Science Club | -- |
| Yankton Swim Team | -- |
| Yankton Womens Childrens Shelter | -- |