| Name | Deductibility Code |
| Beaufort District Center African Methodist Episopal Church | -- |
| Bridging the Gap | -- |
| Calvary Baptist Church of Walterboro | -- |
| Coalition of Business and Industry for Workforce Development | -- |
| Coastal Electric Trust | -- |
| Colleton Center | -- |
| Colleton Christian Womens Job Corps | -- |
| Colleton County Arts Council Incorporated | -- |
| Colleton County Commission on Alcohol and Drug Abuse | -- |
| Colleton County Council on Aging Inc. | -- |
| Colleton County Foster Parent Association | -- |
| Colleton County Historical and Preservation Society | -- |
| Colleton County Literacy Council | -- |
| Colleton Disabilities Foundation | -- |
| Colleton Improvement Collaborative | -- |
| Colleton Preparatory Academy Inc. | -- |
| Colleton Regional Hospital Auxiliary Inc. | -- |
| Colleton Training Colleton High School Alumni Association Inc. | -- |
| Community Missions | -- |
| Eugene Cryer Jr Educational Family Life Center | -- |
| Faith Cathedral Fellowship Inc. | -- |
| Friends of the Colleton County Memorial Library | -- |
| Friends of the Great Swamp Sanctuary | -- |
| Full Gospel Holiness Church of Walterboro | -- |
| Future Vision | -- |
| Great Temple of Ihvh for All Nations Church of God in Christ | -- |
| International Center for Sustainability Inc. | -- |
| Leadership Colleton Alumni Association | -- |
| Light Ministries | -- |
| Living Water Charitable Supporting Organization | -- |
| Living Word Outreach Ministries of Walterboro Incorporated | -- |
| Lowcountry Area Health Education Center | -- |
| Lowcountry Community Action Agency 807 Hampton | -- |
| Lowcountry Community Players Inc. | -- |
| Lowcountry Ladies of South Carolina | -- |
| Lowcountry Resource Conservation and Development | -- |
| Nails in Hand Inc. | -- |
| New Beginnings Wellness Center Inc. | -- |
| New Beginnings Word Ministry | -- |
| No Days Alone | -- |
| Oakman Branch Community Outreach Corporation | -- |
| Robert L Huffines Jr Foundation Inc. | 4 |
| Rocksolid Foundation Inc. | -- |
| Service Net | 4 |
| Sonshine Ministries Incorporated | -- |
| South Carolina Artisans Center | -- |
| South Carolina Presenters Network | -- |
| Spirit of Truth Pentcostal Holiness Church | -- |
| The Phillip Martin Taylor School of Discipline Inc. | -- |
| Transitional Educational Systems Inc. | -- |
| United Way of Bamberg Colleton and Hampton Inc. | -- |
| Veterans Victory Group Inc. | -- |
| Walterboro Christian Center | -- |
| Walterboro Soccer Club Inc. | -- |