| Name | Deductibility Code |
| Animal Shelter of Clarendon County | -- |
| Bible Evangelistic Mission Incorporated | -- |
| Black River Healthcare Inc. | -- |
| Clarendon Christian Learning Center Inc. | -- |
| Clarendon County Commission on Alcohol & Drug Abuse | -- |
| Clarendon County Community Development Corporation Inc. | -- |
| Clarendon County Council on Aging Inc. | -- |
| Clarendon County Disabilities & Special Needs Board | -- |
| Clarendon County Historical Society | -- |
| Clarendon County Mental Retardation Foundation | -- |
| Clarendon County Ministerial Alliance | -- |
| Clarendon School District Two Education Foundation | -- |
| Clarnedon County Tobacco Free Kids Coalition | -- |
| Coastal Plain Rural Health Network | -- |
| Communities in Schools of Clarendon County | -- |
| Creating A Positive Environment to Succeed | -- |
| Cypress Foundation of Clarendon Memorial Hospital Inc. | -- |
| Deliverance Outreach Ministry Inc. | -- |
| Friends of the Library | -- |
| Grace Christian Fellowship Church Inc. | -- |
| Holly Hill Missionary Baptist Church | -- |
| Independence Place Inc. | -- |
| Jehovah Jireh Outreach Ministries | -- |
| Macedonia Community Development Corp | 4 |
| Manning Educational Association | -- |
| Manning Outreach Ministry | -- |
| Masters Place Inc. | -- |
| Old Fellowship Cemetery Trust | 6 |
| Power for Life Inc. | -- |
| Ram Bay Community Development Corporation | 4 |
| Rambay Residential Care Home Inc. | -- |
| Rustic Forward Air Controller Association Inc. | 6 |
| Salvation Ministries | -- |
| Sumter Bluegrass Series Inc. | 4 |
| Swamp Fox Murals Trail Society | -- |
| The Tabernacle of Prasie Worship Pentecostal Holiness Church | -- |
| Tomlinson Alumni Inc. | -- |
| Tri-Vision Housing Corporation | -- |
| Trinity Homes Inc. | -- |
| Turning Point Community Development Corporation | -- |
| United Farmers USA Inc. | -- |
| United Generations Community Youth Dev Corp | 4 |
| United Ministries of Clarendon County | -- |
| Vanguard Residential Services Inc. | -- |
| Womens Unity Club | -- |