| Name | Deductibility Code |
| American Federation Off Martial Arts Inc. | -- |
| April 30th Foundation | 4 |
| Aufricht Foundation Inc. | 4 |
| Bible Missionary Baptist Church | -- |
| Bluffton Area Charities | -- |
| Bluffton Assembly of God Inc. | -- |
| Bluffton Community Center Foundation Inc. | -- |
| Bluffton Community Center Inc. | -- |
| Bluffton Community Library Association Inc. | -- |
| Bluffton Eagles Community Action Committee | -- |
| Bluffton Historical Preservation Society | -- |
| Bluffton Self Help Inc. | -- |
| Briteden Temporary Job Placement Inc. | -- |
| Cancer Awareness Foundation | -- |
| Carolina Companion Animal Organization | -- |
| Chapel Without Walls | -- |
| Community Care Foundation | -- |
| Crane-Marsh Artistic Productions | -- |
| Cross Outreach Ministries Inc. | -- |
| Cross Schools Inc. | -- |
| Cyclone Swimming | 4 |
| Eleanor A and Bernard H Breedlove Foundation | 4 |
| Family Promise of Beaufort County Inc. | -- |
| Friends of Bluffton Dog Parks | -- |
| Friends of the Performing Arts of Sun City Hilton Head | -- |
| Friends of the Rivers | -- |
| Heroes on Horseback | -- |
| Hilton Head Middle All Sports Booster Club Inc. | -- |
| Hospice Care of the Lowcountry Inc. | -- |
| International Institute for Conductive Education | -- |
| Island Chaplain and Friends Inc. | -- |
| Jeff Katon Scholarship Foundation | -- |
| John P and Margaret Mary Brogan Family Foundation | 4 |
| Julies Mission | -- |
| Leone Charitable Foundation | 4 |
| Literacy Volunteers of the Lowcountry Inc. | -- |
| Live Oak Christian Church | -- |
| Low Country Civil War Roundtable | -- |
| Low Country Legal Clinic Inc. | -- |
| Low Country Sports & Development | -- |
| Lutheran Association of Christian Educators | -- |
| May River Montessori | -- |
| May River Theatre Inc. | -- |
| Med-I-Assist Inc. | -- |
| Mercy Ministries to Native America and Beyond Inc. | -- |
| Michael C Riley Elementary Pto | -- |
| New Beginnings Sars Inc. | -- |
| Old Town Museum at Seven Oaks Inc. | -- |
| Palmetto Animal League | -- |
| Palmetto Bluff Foundation | -- |
| Public Tennis Inc. | -- |
| Rowley Foundation Inc. | 4 |
| Running W Retreat Center | -- |
| Russ and Andrea Gullotti Charitable Foundation | 4 |
| Snac Spay Neuter Alliance & Clinic | -- |
| Society of Bluffton Artists Inc. | -- |
| Southern Humane Alliance Inc. | -- |
| Temple Oseh Shalom | -- |
| The Bluffton Crusaders Booster Club Inc. | -- |
| The James B Near Family Foundation | 4 |
| Thorpe Family Foundation Inc. | 4 |
| Tim Malchak Ministries | -- |
| Trustees Garden Club Inc. | -- |
| Week of Champions Inc. | -- |
| Wheels and Meals | -- |
| William C Green Charitable Foundation Trust | 4 |